We are delighted to announce our latest opinion article in Frontiers in Global Women’s Health titled, “The Impact of Informant-Related Characteristics Including Sex/Gender on Assessment of Alzheimer’s Disease Symptoms and Severity.”


Did you know that the Clinical Dementia Rating Scale (CDR) is pivotal in Alzheimer’s disease (AD) staging?


Have you ever wonder which is the impact of the gender of caregiver characteristics on its readout?


Here we discussed how this factor —often overlooked—play a crucial role in the accuracy of this assessment.


Key Takeaways on possible biases:

Dynamics: The informant’s relationship with the patient can significantly affect the perception of the patient’s health status, potentially influencing severity scores.

Sex/Gender Influence: The sex/gender of the informant can also influence dementia assessments in significant ways.

Cultural Lens: Cultural and socioeconomic characteristics can influence how caregivers assess AD symptoms and severity.

These factors are vital in understanding caregiver reports and ensuring precise patient diagnosis and staging, especially when used as primary endpoints in clinical trials.


A heartfelt thank you to the brilliant minds behind this work: Ella Abken,  Laura Castro, Antonella, Maria Teresa Ferretti, and Carmela Tartaglia for their invaluable collaboration. 👏 


#AlzheimersResearch #WomensBrainHealth #NeurodegenerativeDiseases #ClinicalDementiaRating #HealthcareInnovationbias


🤝Donate today to support the advancement of brain and mental health: https://www.womensbrainproject.com/donate/


Link to the publication: https://www.frontiersin.org/articles/10.3389/fgwh.2024.1326881/full

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